The legacy of ZikaPLAN: a transnational research consortium addressing Zika.

Annelies Wilder-Smith ORCID logo; Elizabeth B Brickley ORCID logo; Ricardo Arraes de Alencar Ximenes; Demócrito de Barros Miranda-Filho ORCID logo; Celina Maria Turchi Martelli; Tom Solomon; Bart C Jacobs; Carlos A Pardo ORCID logo; Lyda Osorio; Beatriz Parra; +19 more... Suzannah Lant; Hugh J Willison ORCID logo; Sonja Leonhard; Lance Turtle; Maria Lúcia Brito Ferreira; Rafael Freitas de Oliveira Franca; Louis Lambrechts ORCID logo; Johan Neyts ORCID logo; Suzanne Kaptein ORCID logo; Rosanna Peeling ORCID logo; Deborah Boeras; James Logan ORCID logo; Helen Dolk ORCID logo; Ieda M Orioli ORCID logo; Andreas Neumayr; Trudie Lang; Bonny Baker; Eduardo Massad; Raman Preet; (2022) The legacy of ZikaPLAN: a transnational research consortium addressing Zika. Global Health Action, 14 (sup1). 2008139-. ISSN 1654-9716 DOI: 10.1080/16549716.2021.2008139
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Global health research partnerships with institutions from high-income countries and low- and middle-income countries are one of the European Commission's flagship programmes. Here, we report on the ZikaPLAN research consortium funded by the European Commission with the primary goal of addressing the urgent knowledge gaps related to the Zika epidemic and the secondary goal of building up research capacity and establishing a Latin American-European research network for emerging vector-borne diseases. Five years of collaborative research effort have led to a better understanding of the full clinical spectrum of congenital Zika syndrome in children and the neurological complications of Zika virus infections in adults and helped explore the origins and trajectory of Zika virus transmission. Individual-level data from ZikaPLAN`s cohort studies were shared for joint analyses as part of the Zika Brazilian Cohorts Consortium, the European Commission-funded Zika Cohorts Vertical Transmission Study Group, and the World Health Organization-led Zika Virus Individual Participant Data Consortium. Furthermore, the legacy of ZikaPLAN includes new tools for birth defect surveillance and a Latin American birth defect surveillance network, an enhanced Guillain-Barre Syndrome research collaboration, a de-centralized evaluation platform for diagnostic assays, a global vector control hub, and the REDe network with freely available training resources to enhance global research capacity in vector-borne diseases.


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