Case Report: Multiorgan Involvement with Congenital Zika Syndrome.

Rodrigo Cachay; Alvaro Schwalb ORCID logo; Takashi Watanabe; Doris Guzman; Thomas Jaenisch; Daniel Guillén-Pinto; Eduardo Gotuzzo; (2020) Case Report: Multiorgan Involvement with Congenital Zika Syndrome. American Journal of Tropical Medicine and Hygiene, 103 (4). pp. 1656-1659. ISSN 0002-9637 DOI: 10.4269/ajtmh.20-0421
Copy

We report the case of an infant born with congenital Zika syndrome (CZS). During the largest Zika virus (ZIKV) outbreak in Peru, the mother presented with fever and rash that were confirmed to be due to ZIKV by real-time PCR. The infant was born with severe microcephaly. Imaging revealed corpus callosum dysgenesis, lissencephaly, ventriculomegaly, and calcifications. Mild hypertrophic cardiomyopathy with diastolic dysfunction was reported in the echocardiogram. Valgus deviation of the lower extremities and a left clubfoot were diagnosed at birth. The hip ultrasound showed incipient signs of Graf type II dysplasia. The findings confirm that CZS is a multiorgan phenotype in which microcephaly is merely the tip of the iceberg. A multidisciplinary approach is needed for the evaluation of these children.


picture_as_pdf
Cachay_etal_2020_Multiorgan-involvement-with-congenital-zika.pdf
subject
Published Version
copyright
Available under Copyright the publishers

View Download

Atom BibTeX OpenURL ContextObject in Span Multiline CSV OpenURL ContextObject Dublin Core Dublin Core MPEG-21 DIDL EndNote HTML Citation JSON MARC (ASCII) MARC (ISO 2709) METS MODS RDF+N3 RDF+N-Triples RDF+XML RIOXX2 XML Reference Manager Refer Simple Metadata ASCII Citation EP3 XML
Export

Downloads