Prevalence of new variants of Chlamydia trachomatis escaping detection by the Aptima Combo 2 assay, England, June to August 2019.
David J Roberts;
Grahame S Davis;
Michelle J Cole;
Dixita Naik;
Hitiksha Maru;
Neil Woodford;
Peter Muir;
Paddy Horner;
Ian Simms;
George Thickett;
+8 more...
Paul Crook;
Kirsty Foster;
Nick Andrews;
John Saunders;
Helen Fifer;
Kate Folkard;
O Noel Gill;
incident management team;
(2019)
Prevalence of new variants of Chlamydia trachomatis escaping detection by the Aptima Combo 2 assay, England, June to August 2019.
Eurosurveillance, 24 (38).
pp. 2-6.
ISSN 1560-7917
DOI: 10.2807/1560-7917.ES.2019.24.38.1900557
We identified two new Chlamydia trachomatis (CT) variants escaping Aptima Combo 2 (AC2) assay detection, in clinical specimens of two patients. One had a C1514T mutation the other a G1523A mutation, both within the AC2 23S rRNA target region. The prevalence of such variants among persons tested for CT in England was estimated to be fewer than 0.003%.
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