Initial low-dose oral levothyroxine in a child with Down syndrome, myxedema, and cardiogenic shock.

Annika Janson ORCID logo; CathrinHällström; MagnusIversen; MikaelFinder; AmiraElimam; RicardNergårdh; (2019) Initial low-dose oral levothyroxine in a child with Down syndrome, myxedema, and cardiogenic shock. CLINICAL CASE REPORTS, 7 (7). pp. 1291-1296. ISSN 2050-0904 DOI: 10.1002/ccr3.2169
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Myxedema is extremely rare in children, and guidelines are lacking. We treated a 12-year-old girl with myxedema and cardiogenic shock with initial low dose (0.3-2.5 μg/kg body weight/day) of oral levothyroxine and intensive care. Oral administration may safely revert children's myxedema in a dosage resembling that for hypothyroidism.



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