Temporal trends of SARS-CoV-2 seroprevalence during the first wave of the COVID-19 epidemic in Kenya.
Ifedayo MO Adetifa
;
Sophie Uyoga
;
John N Gitonga;
Daisy Mugo;
Mark Otiende
;
James Nyagwange;
Henry K Karanja;
James Tuju;
Perpetual Wanjiku;
Rashid Aman;
+25 more...
Mercy Mwangangi;
Patrick Amoth;
Kadondi Kasera;
Wangari Ng'ang'a;
Charles Rombo;
Christine Yegon;
Khamisi Kithi;
Elizabeth Odhiambo;
Thomas Rotich;
Irene Orgut;
Sammy Kihara;
Christian Bottomley
;
Eunice W Kagucia
;
Katherine E Gallagher
;
Anthony Etyang;
Shirine Voller
;
Teresa Lambe
;
Daniel Wright
;
Edwine Barasa;
Benjamin Tsofa;
Philip Bejon;
Lynette I Ochola-Oyier;
Ambrose Agweyu
;
J Anthony G Scott
;
George M Warimwe
;
(2021)
Temporal trends of SARS-CoV-2 seroprevalence during the first wave of the COVID-19 epidemic in Kenya.
Nature communications, 12 (1).
3966-.
ISSN 2041-1723
DOI: 10.1038/s41467-021-24062-3
Observed SARS-CoV-2 infections and deaths are low in tropical Africa raising questions about the extent of transmission. We measured SARS-CoV-2 IgG by ELISA in 9,922 blood donors across Kenya and adjusted for sampling bias and test performance. By 1st September 2020, 577 COVID-19 deaths were observed nationwide and seroprevalence was 9.1% (95%CI 7.6-10.8%). Seroprevalence in Nairobi was 22.7% (18.0-27.7%). Although most people remained susceptible, SARS-CoV-2 had spread widely in Kenya with apparently low associated mortality.
ORCID: https://orcid.org/0000-0003-2556-9407
ORCID: https://orcid.org/0000-0003-1746-7873
ORCID: https://orcid.org/0000-0002-1389-1813
ORCID: https://orcid.org/0000-0002-5241-8412
ORCID: https://orcid.org/0000-0002-4481-8889
ORCID: https://orcid.org/0000-0002-5604-7647
ORCID: https://orcid.org/0000-0001-7382-8675
ORCID: https://orcid.org/0000-0001-7711-897X
ORCID: https://orcid.org/0000-0002-8114-1838
ORCID: https://orcid.org/0000-0001-8760-1279
ORCID: https://orcid.org/0000-0001-7533-5006
ORCID: https://orcid.org/0000-0002-4911-6333