Impact of Intrapartum Oral Azithromycin on the Acquired Macrolide Resistome of Infants' Nasopharynx: A Randomized Controlled Trial.
Abdoulie Bojang;
Sarah L Baines;
Bully Camara;
Romain Guerillot;
Liam Donovan;
Raquel Sánchez Marqués;
Ousman Secka;
Umberto D'Alessandro ;
Christian Bottomley ;
Benjamin P Howden;
+1 more...
Anna Roca ;
(2020)
Impact of Intrapartum Oral Azithromycin on the Acquired Macrolide Resistome of Infants' Nasopharynx: A Randomized Controlled Trial.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 71 (12).
pp. 3222-3225.
ISSN 1058-4838
DOI: 10.1093/cid/ciaa609
UNLABELLED: In a post hoc analysis of samples from an intrapartum azithromycin randomized clinical trial, we found that children whose mothers had been treated with the drug had higher prevalence of macrolide-resistance genes msr(A) and ermC at 28 days but not at 12 months. The 2 genes were positively associated in the nasopharynx. CLINICAL TRIALS REGISTRATION: NCT1800942.
Item Type | Article |
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Elements ID | 148017 |
ORCID: https://orcid.org/0000-0001-6341-5009
ORCID: https://orcid.org/0000-0002-5241-8412
ORCID: https://orcid.org/0000-0001-6034-1868