Outcomes of Reflex Cryptococcal Antigen (CrAg) Screening in Human Immunodeficiency Virus (HIV)-Positive Patients With CD4 Counts of 100-200 Cells/µL in Botswana.
Mark W Tenforde;
Thandi Milton;
Ikanyeng Rulaganyang;
Charles Muthoga;
Leabaneng Tawe;
Tom Chiller;
Gregory Greene;
Alexander Jordan;
Christopher G Williams;
Leah Owen;
+5 more...
Tshepo B Leeme;
Amber Boose;
Julia Ngidi;
Madisa Mine;
Joseph N Jarvis ;
(2020)
Outcomes of Reflex Cryptococcal Antigen (CrAg) Screening in Human Immunodeficiency Virus (HIV)-Positive Patients With CD4 Counts of 100-200 Cells/µL in Botswana.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 72 (9).
pp. 1635-1638.
ISSN 1058-4838
DOI: 10.1093/cid/ciaa899
Increasing the CD4-count threshold for cryptococcal antigen (CrAg) screening from ≤100 to ≤200 cells/µL resulted in a 3-fold increase in numbers screened. CrAg-prevalence was 3.5% at CD4 101-200 and 6.2% ≤100 cells/µL. Six-month mortality was 21.4% (9/42) in CrAg-positive CD4 ≤100 cells/µL and 3.2% (1/31) in CrAg-positive CD4 101-200 cells/µL.
Item Type | Article |
---|---|
Elements ID | 148753 |
ORCID: https://orcid.org/0000-0003-1459-5554