Partner Bereavement and Detection of Dementia: A UK-Based Cohort Study Using Routine Health Data.

Harriet J Forbes ORCID logo; Angel YS Wong ORCID logo; Caroline Morton; Krishnan Bhaskaran ORCID logo; Liam Smeeth ORCID logo; Marcus Richards; Sigrun AJ Schmidt; Sinéad M Langan ORCID logo; Charlotte Warren-Gash ORCID logo; (2019) Partner Bereavement and Detection of Dementia: A UK-Based Cohort Study Using Routine Health Data. Journal of Alzheimer's Disease, 72 (2). pp. 653-662. ISSN 1387-2877 DOI: 10.3233/JAD-190571
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BACKGROUND: In the UK, an estimated one third of people with dementia have not received a diagnosis. Good evidence suggests that dementia risk is increased among widowed individuals; however, it is not clear if they are being diagnosed in routine primary care. OBJECTIVE: This study aimed to investigate if bereavement influenced the probability of having received a dementia diagnosis. METHODS: A population-based cohort study using UK electronic health records, between 1997 and 2017, among 247,586 opposite-sex partners. Those experiencing partner bereavement were matched (age, sex, and date of bereavement) to a non-bereaved person living in a partnership. Multivariate cox regression was performed. RESULTS: Partner bereavement was associated with an increased risk of receiving a diagnosis of dementia in the first three months (hazard ratio (HR) 1.43, 95% CI 1.20-1.71) and first six months (HR 1.24, 95% CI 1.09-1.41), while there was a small reduced risk of getting a dementia diagnosis over all follow-up (HR 0.94, 95% CI 0.89-0.98). CONCLUSIONS: Partner bereavement appears to lead to a short-term increased risk of the surviving partner receiving a diagnosis of dementia, suggesting that bereavement unmasks existing undiagnosed dementia. Over the longer term, however, bereaved individuals are less likely to have a diagnosis of dementia in their health records than non-bereaved individuals.


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