The Immunogenicity of Fractional Intradermal Doses of the Inactivated Poliovirus Vaccine Is Associated With the Size of the Intradermal Fluid Bleb.
Jack Bibby;
Yauba Saidu;
Ama Umesi;
Ngozi Moneke-Anyanwoke;
Adedapo O Bashorun;
Mariama Badjie Hydara;
Ikechukwu Adigweme;
Jane U Adetifa;
Michael Okoye;
Elishia Roberts;
+9 more...
Ralf Clemens;
Ananda S Bandyopadhyay;
Abdul K Muhammad;
Sarah Mulwa 
;
Michael Royals;
Courtney Jarrahian;
David Jeffries ;
Beate Kampmann ;
Ed Clarke ;
(2017)
The Immunogenicity of Fractional Intradermal Doses of the Inactivated Poliovirus Vaccine Is Associated With the Size of the Intradermal Fluid Bleb.
CLINICAL INFECTIOUS DISEASES, 65 (5).
pp. 851-854.
ISSN 1058-4838
DOI: 10.1093/cid/cix381
;
Michael Royals;
Courtney Jarrahian;
David Jeffries ;
Beate Kampmann ;
Ed Clarke ;
(2017)
The Immunogenicity of Fractional Intradermal Doses of the Inactivated Poliovirus Vaccine Is Associated With the Size of the Intradermal Fluid Bleb.
CLINICAL INFECTIOUS DISEASES, 65 (5).
pp. 851-854.
ISSN 1058-4838
DOI: 10.1093/cid/cix381
The immunogenicity of fractional (one-fifth, 0.1 mL) intradermal doses of the inactivated poliovirus vaccine (ID fIPV) is positively correlated with the size of the intradermal fluid bleb. Training of vaccinators for campaign and routine ID fIPV administration should focus on generating an 8- to 10-mm bleb with each injection. Clinical Trials Registration NCT01847872.
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