Cryptococcal Meningitis and Tuberculous Meningitis Co-infection in HIV-Infected Ugandan Adults.

Jayne Ellis ORCID logo; Fiona V Cresswell ORCID logo; Joshua Rhein; Kenneth Ssebambulidde; David R Boulware; (2018) Cryptococcal Meningitis and Tuberculous Meningitis Co-infection in HIV-Infected Ugandan Adults. Open forum infectious diseases, 5 (8). ofy193-. ISSN 2328-8957 DOI: 10.1093/ofid/ofy193
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We report 5 HIV-infected Ugandan adults with cryptococcal and tuberculous (TB) meningitis co-infection. All unmasked meningitis occurred within 5 weeks of starting HIV therapy. Xpert MTB/RIF Ultra facilitated prompt diagnosis; however, 60% in-hospital mortality occurred. TB meningitis coinfection prevalence was 0.8% (5/586) among cryptococcal meningitis, 2 during second cryptococcal episodes.


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