Polyspecific Intravenous Immunoglobulin in Clindamycin-treated Patients With Streptococcal Toxic Shock Syndrome: A Systematic Review and Meta-analysis.
Tom Parks;
Clare Wilson;
Nigel Curtis;
Anna Norrby-Teglund;
Shiranee Sriskandan;
(2018)
Polyspecific Intravenous Immunoglobulin in Clindamycin-treated Patients With Streptococcal Toxic Shock Syndrome: A Systematic Review and Meta-analysis.
Clinical infectious diseases, 67 (9).
pp. 1434-1436.
ISSN 1058-4838
DOI: 10.1093/cid/ciy401
We evaluated the effect of intravenous immunoglobulin (IVIG) on mortality in clindamycin-treated streptococcal toxic shock syndrome using a meta-analysis. In association with IVIG, mortality fell from 33.7% to 15.7% with remarkable consistency across the single randomized and four nonrandomized studies.
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