Diabetes mellitus and latent tuberculosis infection: baseline analysis of a large UK cohort.
Charlotte Jackson 
;
Jo Southern;
Ajit Lalvani;
Francis Drobniewski;
Chris J Griffiths;
Marc Lipman;
Graham H Bothamley;
Jonathan J Deeks;
Ambreen Imran;
Onn Min Kon;
+8 more...
Sithembinkosi Mpofu;
Vladyslav Nikolayevskyy;
Melanie Rees-Roberts;
Alice Sitch;
Saranya Sridhar;
Chuen-Yan Tsou;
Hilary Whitworth ;
Ibrahim Abubakar;
(2018)
Diabetes mellitus and latent tuberculosis infection: baseline analysis of a large UK cohort.
Thorax, 74 (1).
pp. 91-94.
ISSN 0040-6376
DOI: 10.1136/thoraxjnl-2017-211124
;
Jo Southern;
Ajit Lalvani;
Francis Drobniewski;
Chris J Griffiths;
Marc Lipman;
Graham H Bothamley;
Jonathan J Deeks;
Ambreen Imran;
Onn Min Kon;
+8 more...
Sithembinkosi Mpofu;
Vladyslav Nikolayevskyy;
Melanie Rees-Roberts;
Alice Sitch;
Saranya Sridhar;
Chuen-Yan Tsou;
Hilary Whitworth ;
Ibrahim Abubakar;
(2018)
Diabetes mellitus and latent tuberculosis infection: baseline analysis of a large UK cohort.
Thorax, 74 (1).
pp. 91-94.
ISSN 0040-6376
DOI: 10.1136/thoraxjnl-2017-211124
We conducted a cross-sectional analysis of baseline data from a UK cohort study which enrolled participants at risk of latent tuberculosis infection (LTBI, defined as a positive result for either of the two interferon gamma release assays). Binomial regression with a log link was used to estimate crude and adjusted prevalence ratios (PRs) and 95% CIs for the relationship between diabetes mellitus (DM) and LTBI. Adjusted for age, sex, ethnicity, body mass index and the presence of other immunocompromising conditions, DM was associated with a 15% higher prevalence of LTBI (adjusted PR=1.15, 95% CI 1.02 to 1.30, p=0.025). TRIAL REGISTRATION NUMBER: PREDICT is registered on clinicaltrials.gov (NCT01162265).
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picture_as_pdf - Jackson-etal-Diabetes-mellitus-and-latent-tuberculosis-infection.pdf
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subject - Accepted Version
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- Available under Creative Commons: NC-ND 3.0
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