Identification of amino acid residues within the N-terminal domain of EspA that play a role in EspA filament biogenesis and function.
Mona P Singh;
Robert K Shaw;
Stuart Knutton;
Mark J Pallen;
Valerie F Crepin;
Gad Frankel;
(2008)
Identification of amino acid residues within the N-terminal domain of EspA that play a role in EspA filament biogenesis and function.
Journal of bacteriology, 190 (6).
pp. 2221-2226.
ISSN 0021-9193
DOI: 10.1128/JB.01753-07
Enteropathogenic Escherichia coli employs a filamentous type III secretion system, made by homopolymerization of the translocator protein EspA. In this study, we have shown that the N-terminal region of EspA has a role in EspA's protein stability, interaction with the CesAB chaperone, and filament biogenesis and function.
| Item Type | Article |
|---|---|
| ISI | 253825500040 |