In Vitro Susceptibility to Closthioamide among Clinical and Reference Strains of Neisseria gonorrhoeae.
Victoria F Miari 
;
Priya Solanki;
Yonek Hleba;
Richard A Stabler ;
John T Heap;
(2017)
In Vitro Susceptibility to Closthioamide among Clinical and Reference Strains of Neisseria gonorrhoeae.
Antimicrobial agents and chemotherapy, 61 (10).
e00929-17.
ISSN 0066-4804
DOI: 10.1128/AAC.00929-17
;
Priya Solanki;
Yonek Hleba;
Richard A Stabler ;
John T Heap;
(2017)
In Vitro Susceptibility to Closthioamide among Clinical and Reference Strains of Neisseria gonorrhoeae.
Antimicrobial agents and chemotherapy, 61 (10).
e00929-17.
ISSN 0066-4804
DOI: 10.1128/AAC.00929-17
Neisseria gonorrhoeae is one of the leading antimicrobial resistance threats worldwide. This study determined the MICs of closthioamide to be 0.008 to 0.5 mg/liter for clinical N. gonorrhoeae strains and related species. Cross-resistance with existing antimicrobial resistance was not detected, indicating that closthioamide could be used to treat drug-resistant N. gonorrhoeae.
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