In vivo demonstration of FNR dimers in response to lower O(2) availability.

Adrian J Jervis; Jeffrey Green; (2007) In vivo demonstration of FNR dimers in response to lower O(2) availability. Journal of bacteriology, 189 (7). pp. 2930-2932. ISSN 0021-9193 DOI: 10.1128/JB.01921-06
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Escherichia coli FNR is an O(2)-sensing transcription factor. In vitro studies indicate that anaerobic iron-sulfur cluster acquisition promotes FNR dimerization. Here, two-hybrid assays show that iron-sulfur cluster-dependent FNR dimers are formed in vivo in response to lower O(2) availability, consistent with the current model of FNR activation.

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