Performance of the BioPlex 2200 multiplexing immunoassay platform for the detection of herpes simplex virus type 2 specific antibodies in African settings.
Jérôme LeGoff;
Gérard Grésenguet;
Chrysostome Gody;
Jean De Dieu Longo;
Nzambi Khonde;
Helen A Weiss ;
Philippe Mayaud ;
Laurent Bélec;
ANRS 12-12 Study Group;
(2011)
Performance of the BioPlex 2200 multiplexing immunoassay platform for the detection of herpes simplex virus type 2 specific antibodies in African settings.
Clinical and vaccine immunology, 18 (7).
pp. 1191-1193.
ISSN 1556-6811
DOI: 10.1128/CVI.05003-11
The BioPlex platform was evaluated for the detection of herpes simplex virus 2 (HSV-2) antibodies in sub-Saharan Africa individuals in comparison to clinicovirological standards and compared to HerpeSelect. The sensitivities and specificities were, respectively, 88.9% and 93.5% for BioPlex and 89.9% and 92.7% for HerpeSelect. The agreement between both assays was 95.7%.
Item Type | Article |
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Keywords | linked immunosorbent assays, placebo-controlled trial, plasma hiv-1, rna, enzyme-immunoassay, genital herpes, women, focus, hsv-2, acyclovir, impact |
ISI | 292378200022 |
ORCID: https://orcid.org/0000-0003-3547-7936
ORCID: https://orcid.org/0000-0001-5730-947X