Performance of the BioPlex 2200 multiplexing immunoassay platform for the detection of herpes simplex virus type 2 specific antibodies in African settings.

Jérôme LeGoff; Gérard Grésenguet; Chrysostome Gody; Jean De Dieu Longo; Nzambi Khonde; Helen A Weiss ORCID logo; Philippe Mayaud ORCID logo; Laurent Bélec; ANRS 12-12 Study Group; (2011) Performance of the BioPlex 2200 multiplexing immunoassay platform for the detection of herpes simplex virus type 2 specific antibodies in African settings. Clinical and vaccine immunology, 18 (7). pp. 1191-1193. ISSN 1556-6811 DOI: 10.1128/CVI.05003-11
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The BioPlex platform was evaluated for the detection of herpes simplex virus 2 (HSV-2) antibodies in sub-Saharan Africa individuals in comparison to clinicovirological standards and compared to HerpeSelect. The sensitivities and specificities were, respectively, 88.9% and 93.5% for BioPlex and 89.9% and 92.7% for HerpeSelect. The agreement between both assays was 95.7%.

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