Capsular Typing Method for Streptococcus agalactiae Using Whole-Genome Sequence Data.

Anna ESheppard; AlisonVaughan; NicolaJones; PaulTurner; ClaudiaTurner; AndroullaEfstratiou; DarshanaPatel; Modernising Medical Microbiology Informatics Group; A SarahWalker; James ABerkley; +2 more... Derrick WCrook; Anna C Seale ORCID logo; (2016) Capsular Typing Method for Streptococcus agalactiae Using Whole-Genome Sequence Data. Journal of clinical microbiology, 54 (5). pp. 1388-1390. ISSN 0095-1137 DOI: 10.1128/JCM.03142-15
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Group B streptococcus (GBS) capsular serotypes are major determinants of virulence and affect potential vaccine coverage. Here we report a whole-genome-sequencing-based method for GBS serotype assignment. This method shows strong agreement (kappa of 0.92) with conventional methods and increased serotype assignment (100%) to all 10 capsular types.
Item Type Article
ISI 374955700036

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