Capsular Typing Method for Streptococcus agalactiae Using Whole-Genome Sequence Data.
Anna E Sheppard;
Alison Vaughan;
Nicola Jones;
Paul Turner;
Claudia Turner;
Androulla Efstratiou;
Darshana Patel;
Modernising Medical Microbiology Informatics Group;
A Sarah Walker;
James A Berkley;
+2 more...
Derrick W Crook;
Anna C Seale 
;
(2016)
Capsular Typing Method for Streptococcus agalactiae Using Whole-Genome Sequence Data.
Journal of clinical microbiology, 54 (5).
pp. 1388-1390.
ISSN 0095-1137
DOI: 10.1128/JCM.03142-15
;
(2016)
Capsular Typing Method for Streptococcus agalactiae Using Whole-Genome Sequence Data.
Journal of clinical microbiology, 54 (5).
pp. 1388-1390.
ISSN 0095-1137
DOI: 10.1128/JCM.03142-15
Group B streptococcus (GBS) capsular serotypes are major determinants of virulence and affect potential vaccine coverage. Here we report a whole-genome-sequencing-based method for GBS serotype assignment. This method shows strong agreement (kappa of 0.92) with conventional methods and increased serotype assignment (100%) to all 10 capsular types.
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