Inter- and intra-assay reproducibility of microplate Alamar blue assay results for isoniazid, rifampicin, ethambutol, streptomycin, ciprofloxacin, and capreomycin drug susceptibility testing of Mycobacterium tuberculosis.
BrianLeonard;
JorgeCoronel;
MarkSiedner;
LouisGrandjean;
LuzCaviedes;
PilarNavarro;
Robert HGilman;
David AJ Moore 
;
(2008)
Inter- and intra-assay reproducibility of microplate Alamar blue assay results for isoniazid, rifampicin, ethambutol, streptomycin, ciprofloxacin, and capreomycin drug susceptibility testing of Mycobacterium tuberculosis.
Journal of clinical microbiology, 46 (10).
pp. 3526-3529.
ISSN 0095-1137
DOI: 10.1128/JCM.02083-07
;
(2008)
Inter- and intra-assay reproducibility of microplate Alamar blue assay results for isoniazid, rifampicin, ethambutol, streptomycin, ciprofloxacin, and capreomycin drug susceptibility testing of Mycobacterium tuberculosis.
Journal of clinical microbiology, 46 (10).
pp. 3526-3529.
ISSN 0095-1137
DOI: 10.1128/JCM.02083-07
The intersample and intrasample variability of the results obtained with the microplate Alamar blue assay for the indirect drug susceptibility testing of Mycobacterium tuberculosis was investigated. Between 1.2 and 8.5% of paired MICs differed by more than one twofold dilution, resulting in discordant susceptible-resistant designations at frequencies between 0.6% (rifampin) and 18.9% (ethambutol).
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- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2566109 (OA Location)
- 10.1128/JCM.02083-07 (DOI)
- 18701659 (PubMed)