Characterization and management of paradoxical upgrading reactions in HIV-uninfected patients with lymph node tuberculosis.
Charlotte R Hawkey;
Timothy Yap;
Janis Pereira;
David AJ Moore 
;
Robert N Davidson;
Geoffrey Pasvol;
Onn Min Kon;
Robert A Wall;
Robert J Wilkinson;
(2005)
Characterization and management of paradoxical upgrading reactions in HIV-uninfected patients with lymph node tuberculosis.
Clinical infectious diseases, 40 (9).
pp. 1368-1371.
ISSN 1058-4838
DOI: 10.1086/429317
;
Robert N Davidson;
Geoffrey Pasvol;
Onn Min Kon;
Robert A Wall;
Robert J Wilkinson;
(2005)
Characterization and management of paradoxical upgrading reactions in HIV-uninfected patients with lymph node tuberculosis.
Clinical infectious diseases, 40 (9).
pp. 1368-1371.
ISSN 1058-4838
DOI: 10.1086/429317
In a retrospective analysis, paradoxical deterioration of lymph node tuberculosis in human immunodeficiency virus-uninfected patients was common, occurring in 25 (23%) of 109 patients after treatment had been given for a median of 46 days (interquartile range, 21-139 days) and persisting for a median of 67.5 days (interquartile range, 34-111 days). We found no association between the use of steroids and the duration of reaction.
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