Rapid assessment of tetanus vaccine-induced immunity in Bangladesh and the Gambia.
G Ramakrishnan;
M Wright;
M Alam;
C Naylor;
M Kabir;
A Zerin;
T Ferdous;
K Pedersen;
BJ Hennig;
JR Donowitz;
+5 more...
R Wegmuller;
R Haque;
WAJr Petri;
J Herbein;
CA Gilchrist;
(2016)
Rapid assessment of tetanus vaccine-induced immunity in Bangladesh and the Gambia.
Diagnostic microbiology and infectious disease.
ISSN 0732-8893
DOI: 10.1016/j.diagmicrobio.2016.11.011
We have developed recombinant fragment C based rapid point of care dipstick devices to assess tetanus immunization status using plasma or whole blood. The devices demonstrated specificity of 0.90 and sensitivity of 0.90 (whole blood)/0.94 (plasma) at field sites in Bangladesh and The Gambia when compared to a commercial ELISA with the immune cut-off titer set as ≥0.1IU/mL.
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picture_as_pdf - 1-s2.0-S0732889316303947-main.pdf
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subject - Accepted Version
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- Available under Creative Commons: NC-ND 3.0
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