Comparison of microarray-predicted closest genomes to sequencing for poliovirus vaccine strain similarity and influenza A phylogeny.
Sebastian Maurer-Stroh;
Charlie WH Lee;
Champa Patel;
Marilla Lucero;
Hanna Nohynek;
Wing-Kin Sung;
Chrysanti Murad;
Jianmin Ma;
Martin L Hibberd;
Christopher W Wong;
+1 more...
Eric AF Simões;
(2015)
Comparison of microarray-predicted closest genomes to sequencing for poliovirus vaccine strain similarity and influenza A phylogeny.
Diagnostic microbiology and infectious disease, 84 (3).
pp. 203-206.
ISSN 0732-8893
DOI: 10.1016/j.diagmicrobio.2015.11.003
We evaluate sequence data from the PathChip high-density hybridization array for epidemiological interpretation of detected pathogens. For influenza A, we derive similar relative outbreak clustering in phylogenetic trees from PathChip-derived compared to classical Sanger-derived sequences. For a positive polio detection, recent infection could be excluded based on vaccine strain similarity.
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