Detection of severe acute respiratory syndrome coronavirus in blood of infected patients.

Lisa FP Ng; Michelle Wong; Susie Koh; Eng-Eong Ooi; King-Fai Tang; Hoe-Nam Leong; Ai-Ee Ling; Lora V Agathe; Jenny Tan; Edison T Liu; +3 more... Ee-Chee Ren; Lee-Ching Ng; Martin L Hibberd; (2004) Detection of severe acute respiratory syndrome coronavirus in blood of infected patients. Journal of clinical microbiology, 42 (1). pp. 347-350. ISSN 0095-1137 DOI: 10.1128/JCM.42.1.347-350.2004
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Severe acute respiratory syndrome (SARS) has caused major outbreaks worldwide, resulting in an urgent need to obtain sensitive and accurate diagnosis of this disease. PCR-based detection methods were developed for use on a variety of samples, including blood. Eighteen subjects were investigated, and results indicated that blood samples contain sufficient virus for detection by using quantitative real-time PCR.

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