Dengue virus surveillance for early warning, Singapore.

Kim Sung Lee; Yee Ling Lai; Sharon Lo; Timothy Barkham; Pauline Aw; Peng Lim Ooi; Ji Choong Tai; Martin Hibberd; Patrik Johansson; Seow Poh Khoo; +1 more... Lee Ching Ng; (2010) Dengue virus surveillance for early warning, Singapore. Emerging infectious diseases, 16 (5). pp. 847-849. ISSN 1080-6040 DOI: 10.3201/eid1605.091006
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In Singapore, after a major outbreak of dengue in 2005, another outbreak occurred in 2007. Laboratory-based surveillance detected a switch from dengue virus serotype 1 (DENV-1) to DENV-2. Phylogenetic analysis showed a clade replacement within DENV-2 cosmopolitan genotype, which accompanied the predominant serotype switch, and cocirculation of multiple genotypes of DENV-3.


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