Site-specific N-terminal labelling of proteins in vitro and in vivo using N-myristoyl transferase and bioorthogonal ligation chemistry.
William P Heal;
Sasala R Wickramasinghe;
Paul W Bowyer;
Anthony A Holder;
Deborah F Smith;
Robin J Leatherbarrow;
Edward W Tate;
(2008)
Site-specific N-terminal labelling of proteins in vitro and in vivo using N-myristoyl transferase and bioorthogonal ligation chemistry.
Chemical communications (Cambridge, England) (4).
pp. 480-482.
ISSN 1359-7345
DOI: 10.1039/b716115h
N-Myristoyl transferase-mediated modification with azide-bearing substrates is introduced as a highly selective and practical method for in vitro and in vivo N-terminal labelling of a recombinant protein using bioorthogonal ligation chemistry.
| Item Type | Article |
|---|---|
| ISI | 252254500017 |