Microscopic Observation Drug Susceptibility Assay for Rapid Diagnosis of Lymph Node Tuberculosis and Detection of Drug Resistance.
Daniela E Kirwan;
Cesar Ugarte-Gil;
Robert H Gilman;
Luz Caviedes;
Hasan Rizvi;
Eduardo Ticona;
Gonzalo Chavez;
José Luis Cabrera;
Eduardo D Matos;
Carlton A Evans;
+3 more...
David AJ Moore 
;
Jon S Friedland;
Lymph Node TB Working Group, Peru;
(2015)
Microscopic Observation Drug Susceptibility Assay for Rapid Diagnosis of Lymph Node Tuberculosis and Detection of Drug Resistance.
Journal of clinical microbiology, 54 (1).
pp. 185-189.
ISSN 0095-1137
DOI: 10.1128/JCM.02227-15
;
Jon S Friedland;
Lymph Node TB Working Group, Peru;
(2015)
Microscopic Observation Drug Susceptibility Assay for Rapid Diagnosis of Lymph Node Tuberculosis and Detection of Drug Resistance.
Journal of clinical microbiology, 54 (1).
pp. 185-189.
ISSN 0095-1137
DOI: 10.1128/JCM.02227-15
In this study, 132 patients with lymphadenopathy were investigated. Fifty-two (39.4%) were diagnosed with tuberculosis (TB). The microscopic observation drug susceptibility (MODS) assay provided rapid (13 days), accurate diagnosis (sensitivity, 65.4%) and reliable drug susceptibility testing (DST). Despite its lower sensitivity than that of other methods, its faster results and simultaneous DST are advantageous in resource-poor settings, supporting the incorporation of MODS into diagnostic algorithms for extrapulmonary TB.
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