Asymmetric PPCys: strongly fluorescing NIR labels.
Georg Michael Fischer;
Christian Jüngst;
Magnus Isomäki-Krondahl;
Dominik Gauss;
Heiko Michael Möller;
Ewald Daltrozzo;
Andreas Zumbusch;
(2010)
Asymmetric PPCys: strongly fluorescing NIR labels.
Chemical communications (Cambridge, England), 46 (29).
pp. 5289-5291.
ISSN 1364-548X
DOI: 10.1039/c0cc00359j
By a stepwise synthesis strategy biofunctionalized Pyrrolopyrrole Cyanines (PPCy) with an asymmetric substitution pattern were obtained. These exhibit extremely strong and narrowband NIR absorption and fluorescence. Internalization of a peptide bound PPCy is demonstrated using live cell microscopy.
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