A cohort study in university students: investigation of risk factors for cytomegalovirus infection.

EJ Patrick; CD Higgins; DH Crawford; KA McAulay; (2013) A cohort study in university students: investigation of risk factors for cytomegalovirus infection. Epidemiology and infection, 142 (9). pp. 1990-1995. ISSN 0950-2688 DOI: 10.1017/S0950268813002720
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Little is known about the main routes of human cytomegalovirus (HCMV) transmission in young adult populations. This study investigated risk factors for HCMV transmission in young adults attending university over a 3-year period. Blood samples were tested for HCMV specific viral capsid antigen IgG by enzyme immunoassay. Being born in a developing country and having lived in Africa were associated with HCMV seropositivity at study onset. No risk factors were associated with HCMV seroconversion over the 3-year follow-up. In contrast to previous reports, sexual activity was not associated with HCMV seroprevalence or seroconversion.

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