Use of spoligotyping for accurate classification of recurrent tuberculosis.

RM Warren; EM Streicher; S Charalambous; G Churchyard; GD van der Spuy; AD Grant

; PD van Helden; TC Victor; (2002) Use of spoligotyping for accurate classification of recurrent tuberculosis. Journal of clinical microbiology, 40 (10). pp. 3851-3853. ISSN 0095-1137 DOI: 10.1128/JCM.40.10.3851-3853.2002

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The spoligotyping method has become an important tool for the tracking of Mycobacterium tuberculosis strains in different epidemiological settings. In this study, we demonstrate the ability of the spoligotyping technique to accurately determine the pathogenetic mechanism of recurrent disease. This methodology has advantages over conventional restriction fragment length polymorphism methods which may be useful in large-scale intervention studies.

Item Type	Article
Keywords	Direct repeat locus, mycobacterium-tuberculosis, complex, strains, is6110, epidemiology, differentiation, markers, contamination, polymorphism, element, Comparative Study, Diagnostic Techniques and Procedures, Human, Mycobacterium tuberculosis, classification, genetics, Polymorphism, Restriction Fragment Length, Recurrence, Support, Non-U.S. Gov't, Tuberculosis, diagnosis, microbiology
ISI	178394800054