Outbreak of aseptic meningitis and mumps after mass vaccination with MMR vaccine using the Leningrad-Zagreb mumps strain.
Sérgio Souza da Cunha;
Laura C Rodrigues;
Maurício L Barreto;
Inês Dourado;
(2002)
Outbreak of aseptic meningitis and mumps after mass vaccination with MMR vaccine using the Leningrad-Zagreb mumps strain.
Vaccine, 20 (7-8).
pp. 1106-1112.
ISSN 0264-410X
DOI: 10.1016/s0264-410x(01)00438-8
Data from routine surveillance during two mass immunisation campaigns (MIC) with Measles-mumps-rubella (MMR)vaccine using Leningrad-Zagreb mumps strain in two states in Brazil were analysed to estimate the risk of vaccine-related meningitis and mumps. Increase in the incidence of the two diseases was observed in both states, 3 weeks after the vaccination campaigns. The estimated number of doses applied per one case of vaccine-related meningitis ranged from 6199 (95% CI: 4854-8058) to 19,247 (95% CI: 12,648-29,513) depending on the diagnostic criteria used and state. It was 300 doses (95% CI: 286-317) for each case of mumps. The implications for vaccination policy are discussed.
| Item Type | Article |
|---|---|
| Keywords | Child, Child, Preschool, *Disease Outbreaks, Human, Infant, Measles-Mumps-Rubella Vaccine/*adverse effects, Meningitis, Aseptic/*epidemiology, Mumps/*epidemiology, Support, Non-U.S. Gov't, Vaccination/*adverse effects, Child, Child, Preschool, Disease Outbreaks, Human, Infant, Measles-Mumps-Rubella Vaccine, adverse effects, Meningitis, Aseptic, epidemiology, Mumps, epidemiology, Support, Non-U.S. Gov't, Vaccination, adverse effects |
| ISI | 173858200017 |