Cissampeloflavone, a chalcone-flavone dimer from Cissampelos pareira.
Irama Ramírez;
Alfredo Carabot;
Pablo Meléndez;
Juan Carmona;
Manuel Jimenez;
Asmita V Patel;
Trevor A Crabb;
Gerald Blunden;
Peter D Cary;
Simon L Croft
;
+1 more...
Manuel Costa;
(2003)
Cissampeloflavone, a chalcone-flavone dimer from Cissampelos pareira.
Phytochemistry, 64 (2).
pp. 645-647.
ISSN 0031-9422
DOI: 10.1016/s0031-9422(03)00241-3
From the aerial parts of Cissampelos pareira L. (Menispermaceae), a chalcone-flavone dimer has been isolated which, mainly from NMR spectroscopic and MS data, was proved to be 2-(4-hydroxy-3-methoxyphenyl)-7-(4-methoxyphenyl)-6-(2-hydroxy-4,6-dimethoxybenzoyl)-furano[3,2-g]benzopyran-4-one. This has been assigned the trivial name cissampeloflavone. The compound has good activity against Trypanosoma cruzi and T. brucei rhodesiense and has a low toxicity to the human KB cell line.
Item Type | Article |
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Keywords | Cissampelos pareira, Menispermaceae, phytochemistry, chalcone-, flavone dimer, cissampeloflavone, antiprotozoal, antitrypanosomal |
ISI | 185421800039 |
ORCID: https://orcid.org/0000-0002-3902-8006