Case report: Schistosoma mansoni infection: failure of standard treatment with praziquantel in a returned traveller.

Stephen D Lawn; Sebastian B Lucas; Peter L Chiodini; (2003) Case report: Schistosoma mansoni infection: failure of standard treatment with praziquantel in a returned traveller. Transactions of the Royal Society of Tropical Medicine and Hygiene, 97 (1). pp. 100-101. ISSN 0035-9203 DOI: 10.1016/s0035-9203(03)90038-1
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Heavy reliance upon praziquantel for the treatment of schistosomiasis raises concerns over potential development of drug resistance. We describe a British traveller who acquired Schistosoma mansoni infection in East Africa and in whom repeated standard 40 mg/kg doses of praziquantel failed to clear the infection despite no opportunity for reinfection.

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