Specific and sensitive diagnosis of schistosome infection: can it be done with antibodies?
Michael J Doenhoff;
Peter L Chiodini;
Joanne V Hamilton;
(2004)
Specific and sensitive diagnosis of schistosome infection: can it be done with antibodies?
Trends in parasitology, 20 (1).
pp. 35-39.
ISSN 1471-4922
DOI: 10.1016/j.pt.2003.10.019
A simple, cheap, sensitive and specific assay for routine diagnosis of schistosome infection is not yet available. This review considers some of the advantages and disadvantages of parasitological microscopy, circulating-antigen detection and antibody-detection methods. Immunoassays for the detection of antibodies reactive against schistosome egg antigens have the potential to be useful in both clinical and epidemiological settings.
Item Type | Article |
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Keywords | linked-immunosorbent-assay, circulating anodic antigen, keyhole, limpet hemocyanin, mansoni egg antigens, cathodic antigen, helminth infections, parasitic diseases, cross-reactivity, low, transmission, worm burden |
ISI | 188226500011 |