Specific and sensitive diagnosis of schistosome infection: can it be done with antibodies?

Michael J Doenhoff; Peter L Chiodini; Joanne V Hamilton; (2004) Specific and sensitive diagnosis of schistosome infection: can it be done with antibodies? Trends in parasitology, 20 (1). pp. 35-39. ISSN 1471-4922 DOI: 10.1016/j.pt.2003.10.019
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A simple, cheap, sensitive and specific assay for routine diagnosis of schistosome infection is not yet available. This review considers some of the advantages and disadvantages of parasitological microscopy, circulating-antigen detection and antibody-detection methods. Immunoassays for the detection of antibodies reactive against schistosome egg antigens have the potential to be useful in both clinical and epidemiological settings.

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