Added value of an oropharyngeal swab in detection of viruses in children hospitalized with lower respiratory tract infection.

Laura L Hammitt; Sidi Kazungu; Steve Welch; Anne Bett; Clayton O Onyango; Rory N Gunson; J Anthony G Scott ORCID logo; D James Nokes; (2011) Added value of an oropharyngeal swab in detection of viruses in children hospitalized with lower respiratory tract infection. Journal of clinical microbiology, 49 (6). pp. 2318-2320. ISSN 0095-1137 DOI: 10.1128/JCM.02605-10
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Paired nasopharyngeal and oropharyngeal swabs collected from 533 children hospitalized with lower respiratory tract infection were assessed by multiplex reverse transcription-PCR. Oropharyngeal swabs increased the number of viral infections detected by 15%, compared to collection of a nasopharyngeal swab alone. This advantage was most pronounced for detection of influenza, parainfluenza, and adenovirus.

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