In-house phage amplification assay is a sound alternative for detecting rifampin-resistant Mycobacterium tuberculosis in low-resource settings.
NorbertoSímboli;
HowardTakiff;
RuthMcNerney;
BeatrizLópez;
AnandiMartin;
Juan CarlosPalomino;
LucíaBarrera;
VivianaRitacco;
(2005)
In-house phage amplification assay is a sound alternative for detecting rifampin-resistant Mycobacterium tuberculosis in low-resource settings.
Antimicrobial agents and chemotherapy, 49 (1).
pp. 425-427.
ISSN 0066-4804
DOI: 10.1128/AAC.49.1.425-427.2005
An in-house mycobacteriophage amplification assay for detecting rifampin-resistant Mycobacterium tuberculosis showed 100% sensitivity, 97.7% specificity, and 95.2% predictive value for resistance in a test of 129 isolates from a hot spot area of multidrug-resistant M. tuberculosis. The applicability of the test was demonstrated in the routine work flow of a low-resource reference laboratory.
Item Type | Article |
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ISI | 226035300057 |
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- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC538913 (OA Location)
- 10.1128/AAC.49.1.425-427.2005 (DOI)
- 15616326 (PubMed)