Chronic inflammatory demyelinating polyradiculoneuropathy: MRI study of brain and spinal cord.

M Laura; W Leong; NMF Murray; G Ingle; KA Miszkiel; DR Altmann; DH Miller; MM Reilly; (2005) Chronic inflammatory demyelinating polyradiculoneuropathy: MRI study of brain and spinal cord. Neurology, 64 (5). pp. 914-916. ISSN 0028-3878 DOI: 10.1212/01.WNL.0000152842.11864.D0
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CNS demyelinating lesions have been reported in chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). There are no studies of cord atrophy in CIDP. Ten patients with CIDP underwent brain and spinal cord MRI to investigate CNS demyelination and cord atrophy. No CNS demyelination was found, but the mean cervical cord area was significantly smaller in CIDP patients vs control subjects. Spinal cord atrophy may be related to degeneration secondary to axonal loss.

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