Statin therapy for primary prevention of cardiovascular disease.

Fiona C Taylor; Mark Huffman; Shah Ebrahim; (2013) Statin therapy for primary prevention of cardiovascular disease. JAMA, 310 (22). pp. 2451-2452. ISSN 0098-7484 DOI: 10.1001/jama.2013.281348
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CLINICAL QUESTION: Do statins reduce rates of cardiovascular events when used for primary prevention? BOTTOM LINE: When used for primary prevention, statins are associated with lower rates of all-cause mortality, major vascular events, and revascularizations compared with placebo. Statin therapy is not associated with increased rates of life-threatening adverse effects such as cancer.

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