DNA vaccines for biodefence.
Helen S Garmory;
Stuart D Perkins;
Robert J Phillpotts;
Richard W Titball;
(2005)
DNA vaccines for biodefence.
Advanced drug delivery reviews, 57 (9).
pp. 1343-1361.
ISSN 0169-409X
DOI: 10.1016/j.addr.2005.01.013
The advantages associated with DNA vaccines include the speed with which they may be constructed and produced at large-scale, the ability to produce a broad spectrum of immune responses, and the ability for delivery using non-invasive means. In addition, DNA vaccines may be manipulated to express multiple antigens and may be tailored for the induction of appropriate immune responses. These advantages make DNA vaccination a promising approach for the development of vaccines for biodefence. In this review, the potential of DNA vaccines for biodefence is discussed.
| Item Type | Article |
|---|---|
| Keywords | immunity, targeting, co-stimulatory molecules, delivery, carriers, regimens, viruses, bacteria, B surface-antigen, recombinant protective antigen, protein, transduction domains, equine encephalitis-virus, raised immune-, responses, cytotoxic t-lymphocyte, plasmid dna, antibody-, responses, gene-gun, yersinia-pestis |
| ISI | 230044000006 |