Long-term clinical outcome of primary progressive MS: predictive value of clinical and MRI data.
J Sastre-Garriga;
GT Ingle;
M Rovaris;
N Téllez;
B Jasperse;
DR Altmann;
B Benedetti;
VL Stevenson;
M Cercignani;
SM Leary;
+10 more...
F Barkhof;
B Brochet;
V Dousset;
M Filippi;
X Montalban;
NF Kalkers;
CH Polman;
A Rovira;
DH Miller;
AJ Thompson;
(2005)
Long-term clinical outcome of primary progressive MS: predictive value of clinical and MRI data.
Neurology, 65 (4).
pp. 633-635.
ISSN 0028-3878
DOI: 10.1212/01.wnl.0000173061.12776.1f
The authors sought to identify clinical and MRI predictors of outcome in primary progressive multiple sclerosis (PPMS). Clinical and MRI assessments were performed at baseline and 2 and 5 years (clinical only). At baseline, disease duration, expanded disability status scale (EDSS) and brain volume predicted outcome. Adding short-term change variables, baseline EDSS, changes in T2* lesion load and cord area, and number of new lesions were predictive. Clinical and MRI variables predict long-term outcome in PPMS.
Item Type | Article |
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ISI | 231371600032 |