Plasmid copy number and disease severity in naturally occurring ocular Chlamydia trachomatis infection.
Anna R Last ;
Chrissy H Roberts ;
EuniceCassama;
MenoNabicassa;
SandraMolina-Gonzalez;
Sarah EBurr;
David CW Mabey ;
Robin L Bailey ;
Martin J Holland ;
(2013)
Plasmid copy number and disease severity in naturally occurring ocular Chlamydia trachomatis infection.
Journal of clinical microbiology, 52 (1).
pp. 324-327.
ISSN 0095-1137
DOI: 10.1128/JCM.02618-13
The Chlamydia trachomatis plasmid is a virulence factor. Plasmid copy number, C. trachomatis load and disease severity were assessed in a treatment-naive population where trachoma is hyperendemic. By using droplet digital PCR, plasmid copy number was found to be stable (median, 5.34 [range, 1 to 18]) and there were no associations with C. trachomatis load or disease severity.
Item Type | Article |
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ISI | 329222400051 |
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- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3911420 (OA Location)
- 10.1128/JCM.02618-13 (DOI)
- 24197878 (PubMed)
ORCID: https://orcid.org/0000-0001-8730-9323
ORCID: https://orcid.org/0000-0003-1064-5980
ORCID: https://orcid.org/0000-0002-0031-8276
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