HLA-A, -B, -C, -DRB1, DRB3, DRB4, DRB5 and DQB1 polymorphism detected by PCR-SSP in a semi-urban HIV-positive Ugandan population.
P Krausa;
S McAdam;
M Bunce;
J Whitworth;
B Biryahwaho;
N French;
B Tugume;
C Gilks;
F Gotch;
(2001)
HLA-A, -B, -C, -DRB1, DRB3, DRB4, DRB5 and DQB1 polymorphism detected by PCR-SSP in a semi-urban HIV-positive Ugandan population.
Experimental and clinical immunogenetics, 16 (1).
pp. 17-25.
ISSN 0254-9670
DOI: 10.1159/000019091
PCR-SSP was used to HLA-type a cohort of Ugandan HIV-positive individuals. The results represent a more comprehensive description of HLA in an African population than previously described and are in concordance with data from a general Black population. Substantial differences exist between this population and Caucasoid populations in which immunological responses to HIV have been investigated; this emphasises that the main HLA-restrictive elements for HIV-specific cytotoxic T lymphocytes will most likely be different for each population.
| Item Type | Article |
|---|---|
| ISI | 79474500003 |