Miltefosine: issues to be addressed in the future.
J Berman;
ADM Bryceson;
S Croft 
;
J Engel;
W Gutteridge;
J Karbwang;
H Sindermann;
J Soto;
S Sundar;
JA Urbina;
(2006)
Miltefosine: issues to be addressed in the future.
Transactions of the Royal Society of Tropical Medicine and Hygiene, 100 Su.
S41-S44.
ISSN 0035-9203
DOI: 10.1016/j.trstmh.2006.02.009
;
J Engel;
W Gutteridge;
J Karbwang;
H Sindermann;
J Soto;
S Sundar;
JA Urbina;
(2006)
Miltefosine: issues to be addressed in the future.
Transactions of the Royal Society of Tropical Medicine and Hygiene, 100 Su.
S41-S44.
ISSN 0035-9203
DOI: 10.1016/j.trstmh.2006.02.009
Future issues that need to be addressed for miltefosine are efficacy against non-Indian visceral leishmaniasis, efficacy in HIV-coinfected patients, efficacy against the many forms of cutaneous and mucosal disease, effectiveness under clinical practice conditions, generation of drug resistance and the need to provide a second antileishmanial agent to protect against this disastrous event, and the ability to maintain reproductive contraceptive practices under routine clinical conditions.
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